Category: RhBMP 2

Alveolar cleft repair using rhBMP-2 avoiding autobone graft

1/2/2016

A 6-year-old girl was brought to our hospital by her parents for surgical correction of her cleft defect. Her cleft lip and cleft palate defect was operated elsewhere, in her childhood.
Maxillofacial Surgeon Dr. S.M. Balaji performed the alveolar cleft repair using rhBMP-2 avoiding bone grafting. Miracle protein rhBMP-2 is a bioengineered version of a protein that occurs in the body. When placed in the cleft defect, it stimulates the body’s stem cells to form new bone and thereby healing the bony defect in the teeth bearing region of the upper jaw. By using rhBMP-2, bone graft surgery from the hip or rib is avoided, thereby avoiding an additional surgery & unsightly scars.

Alveolar cleft defect

Unilateral cleft alveolus defect

3D CBCT scan showing alveolar cleft defect in left side upper jaw

Retained deciduous teeth extracted

rhBMP-2 placed in alveolar cleft avoiding bone graft

Immediately after surgery-surgical site sutured

After surgery following 3 months-3D CBCT scan showing good bone healing and complete closure of alveolar cleft defect

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Successful union of cleft bone into a single jaw bone using miracle protein rhBMP-2

12/6/2015

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An 8 year old boy with bilateral cleft lip and palate defect from Bihar was brought to our hospital with his parents for closure of the cleft defect in the teeth bearing region of upper jaw bone and further rehabilitation of his cleft deformity. The primary cleft lip and palate repair was done elsewhere.
The premaxilla was separated from rest of the alveolus which can be clearly appreciated in 3D CBCT scan. Thus upper alveolus was separated into three different parts which will severely affect the development of teeth later.
Maxillofacial Surgeon Dr. S. M. Balaji performed the premaxillary setback procedure with rhBMP-2 which helps in uniting the three parts into a single jaw bone with new bone formation. This surgery helped for proper growth and development as well as alignment of his teeth.

Intraoperative view showing separate premaxilla due to bilateral cleft defect

3D CBCT scan showing detached and forwardly placed premaxilla from rest of the alveolus

Miracle bone protein rhBMP2 placed in the cleft region to induce new bone formation

Premaxillary segment aligned with the rest of the alveolus and stabilized

Immediately after suturing the gingivomucoperiosteal flap

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Successful premaxillary setback and complete closure of huge alveolar cleft using miracle protein rhBMP-2 in a bilateral cleft lip and palate boy

8/4/2015

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An 8-year-old boy born with bilateral cleft lip and palate reported to our hospital seeking specialized treatment for her cleft defect in the alveolar bone (teeth bearing region of upper jaw). He was previously operated for cleft lip & cleft palate elsewhere.

Due to the bilateral cleft, his maxilla or upper jaw bone was in 3 parts. Anterior segment (premaxilla) was so much forwardly placed. Maxillofacial Surgeon Dr. S.M. Balaji performed the alveolar cleft reconstruction using the miracle protein rhBMP-2 following premaxillary setback. This protein stimulates the body’s own cells to rapidly form new bone at the site of placement. Following surgery, there will be complete bone fill in the cleft defects thereby joining the 3 segments into a single complete maxilla.

By using this revolutionary technology, additional bone graft surgery and scarring at the graft site is avoided. Dr. Balaji has successfully used this novel protein in complete reconstruction of several facial bone defects.

3D CBCT scan view showing detached premaxilla due to cleft defect

During surgery complete separation of premaxilla with that of the maxilla was exposed

Following premaxillary setback alveolar cleft defect was closed with rhBMP2 bone protein

Alveolar cleft defect was corrected by placing miracle bone protein rhBMP2

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Successful reconstruction of alveolar cleft into a single jaw bone using miracle bone protein rhBMP-2

9/3/2015

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A 3 year old boy with unilateral cleft lip and palate defect from Bihar was brought to our hospital by his parents for closure of the cleft defect in the teeth bearing region of upper jaw bone. He was previously operated for cleft lip and cleft palate. Due to the cleft defect, upper alveolus was in two parts which will severely affect the development of teeth later.

Maxillofacial Surgeon Dr. S. M. Balaji performed the cleft alveolus closure with rhBMP-2 which helps in uniting the two parts into a single jaw bone with new bone formation. This surgery helped for proper growth and development as well as alignment of his teeth later.

Preoperative intraoral view showing alveolar cleft defect in left side

Preoperative digital orthopantomogram showing cleft alveolus in left side

Intraoperative view showing alveolar cleft after raising gingivomucoperiosteal flap

rhBMP-2 placed in the alveolar cleft region to induce new bone formation

Immediately after suturing

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Alveolar cleft repair using rhBMP-2 avoiding bone graft

6/12/2014

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An 8-year-old boy was brought to our hospital by his parents for surgical correction of his cleft defect. His cleft lip and cleft palate defect was operated by Maxillofacial Surgeon Dr. S.M. Balaji, in his childhood.

Dr. Balaji performed the alveolar cleft repair using rhBMP-2 avoiding bone grafting. Miracle protein rhBMP-2 is a bioengineered version of a protein that occurs in the body. When placed in the cleft defect, it stimulates the body’s stem cells to form new bone and thereby healing the bony defect in the teeth bearing region of the upper jaw. By using rhBMP-2, bone graft surgery from the hip or rib is avoided, thereby avoiding an additional surgery & unsightly scars.

Preoperative CBCT scan image showing unilateral alveolar cleft in left side of the maxilla

Preoperative intraoral view showing cleft alveolus in the left side of the upper jaw

Gingivomucoperiosteal flap raised and alveolar cleft defect was exposed

Miracle protein rhBMP-2 was placed in the alveolar cleft defect to induce the new bone formation

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Miracle protein rhBMP-2 for alveolar cleft closure avoiding bone grafting

20/10/2014

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A 5-year-old girl from Kerala, born with bilateral cleft lip and palate reported to our hospital seeking specialized correction for her cleft defect in the upper alveolar bone (teeth bearing region of jaw). She was previously operated for cleft lip & cleft palate.

Due to the bilateral cleft defect, the child’s upper jaw bone was in 3 parts. Maxillofacial Surgeon Dr. S.M. Balaji employed an advanced technology to close the alveolar cleft. Collagen sponge soaked in miracle protein rhBMP-2 was placed in the cleft site which stimulates the body’s own cells to rapidly form new bone thereby joining the 3 segments into a single complete bone. With this, a second surgery for bone graft and unsightly scarring at the graft site is avoided. Dr. Balaji has successfully used this novel protein in complete reconstruction of several facial bone defects.

Preoperative intraoral view showing cleft separating premaxilla from the alveolus

3D CBCT scan showing detached and forwardly placed premaxilla from rest of the alveolus

During procedure premaxillary segement was mobilized and the cleft alveolus was exposed

Miracle protein rhBMP-2 was placed in the alveolar cleft defect to induce new bone formation

Gingivomucoperiosteal flap was sutured and the cleft defect was completely sealed with BMP protein

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Miracle protein rhBMP-2, bone graft and implants placed to replace missing teeth in deficient jaw bone

30/9/2014

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A 45-year-old man from Australia came to our hospital seeking fixed replacement of his multiple missing teeth. The loss of many teeth over a long time led to progressive shrinkage of the jaw bone. The height of bone in the lower jaw was inadequate to place implants. Doctors elsewhere advised only removable dentures but the patient wanted fixed teeth to be able to chew and speak comfortably without the fear of dentures slipping off.

Maxillofacial Surgeon & Implantologist Dr. S.M. Balaji successfully reconstructed the deficient jaw using rhBMP-2 and bone graft to enable placement of implants and fixed teeth. The broken upper front teeth were extracted and immediate implants were placed in the same sockets without any bone loss. Implants were also placed in the right upper jaw. Implants and rhBMP-2 protein were placed in the lower jaw. This miracle protein stimulates the body’s own cells to form new bone thereby augmenting the jaw.

A costochondral rib graft was harvested & used to reconstruct the deficient height of the lower jaw and implants were placed. Subsequently, ceramic crowns closely resembling natural teeth will be fixed to the implants to complete the rehabilitation. The patient was very happy that he will have fixed teeth that will help him chew foods easily & give him a beautiful smile.

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Alveolar cleft repair using rhBMP-2 avoiding autobone graft

Successful union of cleft bone into a single jaw bone using miracle protein rhBMP-2

Successful premaxillary setback and complete closure of huge alveolar cleft using miracle protein rhBMP-2 in a bilateral cleft lip and palate boy

Successful reconstruction of alveolar cleft into a single jaw bone using miracle bone protein rhBMP-2

Alveolar cleft repair using rhBMP-2 avoiding bone graft

Miracle protein rhBMP-2 for alveolar cleft closure avoiding bone grafting

Miracle protein rhBMP-2, bone graft and implants placed to replace missing teeth in deficient jaw bone

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